Understanding Glanzmann's Thrombasthenia (GT)
Glanzmann's Thrombasthenia (GT) is a rare genetic disorder that affects the blood's ability to clot. This condition is characterized by the malfunction of platelets, the blood cells crucial for clotting. Individuals with GT often experience abnormal and sometimes severe bleeding. If left untreated or if treatment is unsuccessful, the bleeding associated with GT can pose life-threatening risks.
Delving Deeper into GT
First identified in 1918, GT's impact starts to manifest in early childhood. Individuals with GT may experience severe, intermittent bleeding from the mucous membranes. In some instances, this can escalate to gastrointestinal bleeding and intracranial hemorrhage.
Women with GT often face unique challenges, such as heavy or prolonged menstrual bleeding (menorrhagia) and excessive bleeding during childbirth. Diagnostic blood tests for GT typically reveal an extended bleeding time and a lack of platelet aggregation.
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