A large U.S. study is providing new insight into how common Glanzmann Thrombasthenia (GT) may be and how the condition affects people in everyday life. Researchers analyzed health records from 1,059 people with Glanzmann Thrombasthenia using a large healthcare database containing records from hospitals and clinics across the United States. The study examined GT prevalence, […]
People with Glanzmann Thrombasthenia (GT) can experience repeated bleeding throughout their lives. Over time, that blood loss can contribute to iron deficiency and iron deficiency anemia (IDA). A study published in Hemophilia examined how often iron deficiency anemia occurred and how clinicians managed bleeding in children and young people with GT and Bernard-Soulier syndrome (BSS). […]
As a patient with Glanzmann thrombasthenia, your experience has value. Rare disease patient surveys can help researchers understand daily challenges, treatment burdens, and patient priorities. Before participating, it is important to understand how your information will be used, who can access it, and what privacy protections apply. How Will Your Patient Data Be Used and […]
Glanzmann Thrombasthenia (GT) is a rare inherited bleeding disorder in which platelets do not work normally. While platelet numbers are typically normal, the platelets have difficulty sticking together, or aggregating, to help stop bleeding. Learn more about Glanzmann Thrombasthenia and the resources available through Glanzmann’s Research Foundation. The symptoms of Glanzmann Thrombasthenia can look very […]
Can women with Glanzmann Thrombasthenia have a successful pregnancy? Yes. Pregnancy is possible for women with Glanzmann Thrombasthenia (GT), but it is considered high risk and requires careful planning and specialized care. Because GT affects the ability of platelets to aggregate normally, pregnancy and childbirth can present significant bleeding challenges. Some women may also develop […]
Glanzmann Thrombasthenia (GT) is usually described as a platelet function disorder. People with GT generally have a normal platelet count, but those platelets cannot properly stick together to form a stable clot. New research published in Blood suggests the story may be more complicated. Researchers found evidence that the proteins affected in Glanzmann Thrombasthenia may […]
Severe bleeding can be especially difficult to manage in people with Glanzmann Thrombasthenia (GT) when the source of the bleeding cannot be controlled through conventional treatment. A 2026 case report describes a 66-year-old man with Glanzmann Thrombasthenia who developed life-threatening blood in his urine caused by multiple rare vascular tumors in his bladder. After the […]
People with Glanzmann Thrombasthenia (GT) already have impaired platelet aggregation, so medications that can further affect platelet function deserve careful consideration. One important group of medications is selective serotonin reuptake inhibitors (SSRIs), which are commonly prescribed for depression and anxiety. Research has shown that some antidepressants, particularly SSRIs, can affect platelet function and may be […]
Researchers have reached another encouraging milestone in developing a potential gene therapy for Glanzmann Thrombasthenia (GT). In laboratory testing, an experimental gene-transfer strategy successfully increased production of the platelet receptor that is missing or does not function properly in people with GT. The results support moving the research into stem cells collected from patients with […]
Pregnancy can require additional planning for women with inherited bleeding disorders, including Glanzmann’s Thrombasthenia (GT). A new 2026 study published in SAGE Open Medicine provides additional data on maternal, fetal, and neonatal outcomes among women with inherited bleeding disorders. The study found higher rates of maternal bleeding complications and fetal/neonatal mortality among women with inherited […]
A new 2026 research letter describes an extremely rare case of a patient diagnosed with both Glanzmann thrombasthenia (GT) and von Willebrand disease (VWD). The patient was diagnosed with GT at age five after experiencing bleeding symptoms beginning in infancy. Later, she developed recurrent gastrointestinal bleeding. At age 20, a severe GI bleed did not […]
A newly published case report describes a woman with Glanzmann Thrombasthenia (GT) who developed life threatening bleeding after routine periodontal (gum) treatment despite receiving recommended preventive treatment with recombinant Factor VIIa (NovoSeven). The patient had significant periodontal inflammation before treatment. Although she received standard preventive care, including recombinant Factor VIIa and local bleeding control measures, […]